How long until someone has pain relief with a prolotherapy treatment?

Pain relief varies quite a bit, depending on the patient. Some patients get an immediate response. I had a Division I hockey player who hadn’t played hockey for six months due to lower back pain. I gave him one prolotherapy injection. He came back to me a week later for the second injection. I asked him if he had any pain. He said, “Doc, I feel fine.” I said go ahead and skate. He came back a week later, he still felt fine. I only gave him one injection and he got relief. Now, this is not typical for prolotherapy. Usually it takes three to five injections; some people start to feel some relief during the injection process. However, you can’t be sure it works until you wait a full eight weeks after the last injection.